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Essential Biochemistry - Enzymes (Section 1 - No. 38)

What is the effect of an irreversible inhibitor on an enzyme?
It binds non-covalently to the active site.
It permanently inactivates the enzyme.
It decreases the Km value.
It increases the Vmax value.

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Irreversible inhibitors permanently inactivate an enzyme, usually through covalent modification.

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